Upregulation of CircCSPP1, CircNRIP1, and CircSMAD2 in Breast Cancer and Their Potential as Diagnostic Biomarkers.
: This is the first paper that reports the upregulation of circCSPP1 and circSMAD2 in BC and upregulation of circCSPP1 and circNRIP1 in the triple-negative subgroup. Our findings suggest that circCSPP1, circNRIP1, and circSMAD2 may serve as promising diagnostic biomarkers for BC. Identifying the downstream pathways regulated by these circRNAs could lead to the discovery of new therapeutic targets.
Authors
- Nima Rezaei (ORCID: https://orcid.org/0000-0002-3836-1827)
- Rangarirai Makuku (ORCID: https://orcid.org/0000-0003-3305-2053)
- Farzaneh Darbeheshti
- Parmida Sadat Pezeshki (ORCID: https://orcid.org/0000-0003-2817-4734)
- Mahsa Keshavarz‐Fathi (ORCID: https://orcid.org/0000-0001-8226-5878)
- Yaser Mansoori (ORCID: https://orcid.org/0000-0002-9101-5552)
- Ali Mohammad Mosadeghrad (ORCID: https://orcid.org/0000-0002-7955-6292)
- Homa Seyedmirzaei (ORCID: https://orcid.org/0000-0001-7799-9332)
Institutions
- Universal Scientific Education and Research Network (IR)
- Children's Medical Center (IR)
- Fasa University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-05-01
- DOI
- https://doi.org/10.61186/ibj.4945
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00