Causal relationship between gut microbiota and diabetes based on Mendelian randomization.

This study identified specific gut microbial taxa that may significantly increase or decrease the risk of developing diabetes. Some findings were fully replicated in independent validation datasets. However, the underlying biological mechanisms of these causal relationships warrant further investigation through mechanistic studies and population-based research.

Authors

Jiapeng Tang (ORCID: https://orcid.org/0000-0002-6612-8985)
Tingting Wang (ORCID: https://orcid.org/0000-0001-8051-405X)
Jiabi Qin (ORCID: https://orcid.org/0000-0002-9360-4991)
Manjun Luo
Ziye Li (ORCID: https://orcid.org/0009-0006-7816-5341)
Mengting Sun (ORCID: https://orcid.org/0000-0002-8517-8451)

Institutions

Central South University (CN)
Kunming Medical University (CN)

Publication Details

Journal: PubMed
Published: 2025-03-28
DOI: https://doi.org/10.11817/j.issn.1672-7347.2025.240555
Primary Topic: Gut microbiota and health
Type: article
Field-Weighted Citation Impact: 0.00

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article

Causal relationship between gut microbiota and diabetes based on Mendelian randomization.

Jiapeng Tang, Tingting Wang, Jiabi Qin, Manjun Luo et al.

Mar 28, 2025

1 links

PubMed

Gut microbiota and health

article

Causal relationship between gut microbiota and diabetes based on Mendelian randomization.

Jiapeng Tang, Tingting Wang, Jiabi Qin, Manjun Luo, Ziye Li, Mengting Sun

March 28, 2025article en

Abstract

This study identified specific gut microbial taxa that may significantly increase or decrease the risk of developing diabetes. Some findings were fully replicated in independent validation datasets. However, the underlying biological mechanisms of these causal relationships warrant further investigation through mechanistic studies and population-based research.

PubMedVol. 50(3)

Central South University (CN), Kunming Medical University (CN)

Openalex Percentile: Top 85%

Gut microbiota and health

DOI Source OpenAlex

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