Toxicity assessment of methacryloyloxyethyl phosphorylcholine/selenium nanocomposite in case of oral squamous cell carcinoma

The Taguchi method was used to determine the optimal conditions for obtaining methacryloyloxyethylphosphorylcholine/selenium (MPC/selenium) nanocomposites and to investigate their anticancer activity on oral squamous cell carcinoma (OSCC) cells. The MTT test was used to assess the cytotoxicity and viability of OSCC cells at different concentrations of MPC/selenium. Due to their high anticancer activity (94.9%), the developed nanocomposites can be used as new therapeutic agents in the treatment of oral squamous cell carcinoma.