Blood Management and Conservation During Adult Spine Deformity Surgery

Study DesignNarrative literature review.ObjectivesTo summarize the evidence for perioperative blood conservation for patients undergoing surgery for adult spine deformity.MethodsA systematic literature review with narrative analysis was conducted to describe the evidence for blood conservation strategies before, during and after surgery for adult spine deformity. The evidence is critically analyzed and recommendation drawn.ResultsThe evidence for iron supplementation, autologous blood donation, screening for diatheses, the constitution of the surgical team, hypotensive anaesthesia, osteotomy, patient positioning, antifibrinolytics, transfusion thresholds, cell salvage, surgical technique, topical hemostasis, postoperative drainage, postoperative tranexamic acid and the management of thromboprophylaxis and anticoagulants is critically evaluated. The management of haemorrhage in surgery for adult spine deformity is complex and multifaceted, requiring the surgeon to consider tactics in conservation at every stage of the process. There is a paucity of evidence for many techniques, whilst hypotensive anaesthesia, tranexamic acid, surgical team members and surgical duration have the most significant effects on blood loss and transfusion requirements.ConclusionsThe astute surgeon must consider strategies to prevent excessive haemorrhage in the pre- intra- and postoperative phases of care. Although some commonly used techniques have robust evidence, others may be at best poorly evidenced, and at worst ineffective. Surgeons should consider the members of the operative team, minimizing surgical time, preoperative correction of anemia, hypotensive anesthesia and the use of intravenous and topical tranexamic acid at a minimum.

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Publication Details

Journal
Global Spine Journal
Published
2025-07-01
DOI
https://doi.org/10.1177/21925682231188810
Primary Topic
Spinal Hematomas and Complications
Type
article
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article

Blood Management and Conservation During Adult Spine Deformity Surgery

Lawrence G. Lenke, Thorsten Jentzsch, So Kato, Colby Oitment et al.
Global Spine Journal
Spinal Hematomas and Complications
article

Blood Management and Conservation During Adult Spine Deformity Surgery

Lawrence G. Lenke, Thorsten Jentzsch, So Kato, Colby Oitment, Anna Rienmüller, Christopher I. Shaffrey, Christopher J. Nielsen, Justin S. Smith, Allan R. Martin, Stephen J. Lewis, Brett Rocos
article en

Abstract

Study DesignNarrative literature review.ObjectivesTo summarize the evidence for perioperative blood conservation for patients undergoing surgery for adult spine deformity.MethodsA systematic literature review with narrative analysis was conducted to describe the evidence for blood conservation strategies before, during and after surgery for adult spine deformity. The evidence is critically analyzed and recommendation drawn.ResultsThe evidence for iron supplementation, autologous blood donation, screening for diatheses, the constitution of the surgical team, hypotensive anaesthesia, osteotomy, patient positioning, antifibrinolytics, transfusion thresholds, cell salvage, surgical technique, topical hemostasis, postoperative drainage, postoperative tranexamic acid and the management of thromboprophylaxis and anticoagulants is critically evaluated. The management of haemorrhage in surgery for adult spine deformity is complex and multifaceted, requiring the surgeon to consider tactics in conservation at every stage of the process. There is a paucity of evidence for many techniques, whilst hypotensive anaesthesia, tranexamic acid, surgical team members and surgical duration have the most significant effects on blood loss and transfusion requirements.ConclusionsThe astute surgeon must consider strategies to prevent excessive haemorrhage in the pre- intra- and postoperative phases of care. Although some commonly used techniques have robust evidence, others may be at best poorly evidenced, and at worst ineffective. Surgeons should consider the members of the operative team, minimizing surgical time, preoperative correction of anemia, hypotensive anesthesia and the use of intravenous and topical tranexamic acid at a minimum.

Global Spine JournalVol. 15(3_suppl)
NewYork–Presbyterian Hospital (US), Duke University (US), University of Toronto (CA), University of Zurich (CH), AO Foundation (CH), Toronto Western Hospital (CA), Columbia University Irving Medical Center (US), Hamilton General Hospital (CA), Texas Health Dallas (US), University of Tokyo Hospital (JP), Knowledge Foundation (SE), Neurological Surgery (US), University of Virginia (US), Medical University of Vienna (AT), Hamilton Health Sciences (CA), University of California, Davis (US)
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Openalex Percentile: Top 72%
Spinal Hematomas and Complications
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