Total Synthesis of Nocarterphenyl A

Abstract The total synthesis of Nocarterphenyl A (NCT‐A) was accomplished in nine steps, starting from the commercially available and cost‐effective 2‐methoxy‐4‐nitrophenol. A key feature of the synthetic route is the construction of the thiazole core, which was achieved through a sequence of strategically designed transformations. Critical steps in the synthesis include selective bromination, ester reduction, TBDMS protection, and deprotection, and a final Suzuki–Miyaura cross‐coupling reaction. This convergent and efficient strategy ultimately furnished Nocarterphenyl A in good overall yield.