Factors Associated with Initial Treatment Failure in Inpatients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cohort Study

Home oxygen therapy, high neutrophil count, and acidemia on admission were risk factors for treatment failure. Particularly, patients receiving home oxygen therapy were at a higher risk of treatment failure with the use of narrow-spectrum antibiotics.

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Publication Details

Journal
International Journal of COPD
Published
2025-07-01
DOI
https://doi.org/10.2147/copd.s516855
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
Field-Weighted Citation Impact
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article

Factors Associated with Initial Treatment Failure in Inpatients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cohort Study

Kuniaki Hirai, Mari Kogo, Masayuki Ohbayashi, Miki Takenaka Sato et al.
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International Journal of COPD
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Factors Associated with Initial Treatment Failure in Inpatients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cohort Study

Kuniaki Hirai, Mari Kogo, Masayuki Ohbayashi, Miki Takenaka Sato, Noriko Kohyama, Hironori Sagara
article en

Abstract

Home oxygen therapy, high neutrophil count, and acidemia on admission were risk factors for treatment failure. Particularly, patients receiving home oxygen therapy were at a higher risk of treatment failure with the use of narrow-spectrum antibiotics.

International Journal of COPDVol. Volume 20
SHOWA Medical University (JP)
Good health and well-being
Openalex Percentile: Top 74%
Chronic Obstructive Pulmonary Disease (COPD) Research
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