Elevated Methylation Contributes to Suppressed Expression of Special AT‐Rich Sequence‐Binding Protein 2 in Colorectal Cancer: A Gene‐Disease Association Study

In summary, increased methylation levels contribute to decreased SATB2 expression in CRC, indicating the clinical relevance of SATB2 methylation as a potential therapeutic target for CRC.

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Publication Details

Journal
Health Science Reports
Published
2025-07-01
DOI
https://doi.org/10.1002/hsr2.71056
Primary Topic
Epigenetics and DNA Methylation
Type
article
Field-Weighted Citation Impact
0.00
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article

Elevated Methylation Contributes to Suppressed Expression of Special AT‐Rich Sequence‐Binding Protein 2 in Colorectal Cancer: A Gene‐Disease Association Study

Lei Wei, Cong Lu, Kai Wang, Xiaoyu Feng et al.
Health Science Reports
Epigenetics and DNA Methylation
article

Elevated Methylation Contributes to Suppressed Expression of Special AT‐Rich Sequence‐Binding Protein 2 in Colorectal Cancer: A Gene‐Disease Association Study

Lei Wei, Cong Lu, Kai Wang, Xiaoyu Feng, Lianzheng Su, Dianfang Wei, Weitong Cui, Shuai Li, Chao Song, Huaru Xue
article en

Abstract

In summary, increased methylation levels contribute to decreased SATB2 expression in CRC, indicating the clinical relevance of SATB2 methylation as a potential therapeutic target for CRC.

Health Science ReportsVol. 8(7)
Central Hospital of Zibo (CN)
Good health and well-being
Openalex Percentile: Top 85%
Epigenetics and DNA Methylation
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