Effect of <i>N</i>‐Acetylcysteine, Ascorbic Acid, and a Vitamin E Analog on Oxidative and Storage Lesions in Canine Packed Red Blood Cells

The addition of AA and a VE to canine pRBCs reduced ROS accumulation but did not prevent glutathione depletion during routine storage. Further studies using antioxidants as additives in canine pRBCs are warranted.

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Publication Details

Journal
Journal of Veterinary Emergency and Critical Care
Published
2025-05-01
DOI
https://doi.org/10.1111/vec.70002
Primary Topic
Heme Oxygenase-1 and Carbon Monoxide
Type
article
Field-Weighted Citation Impact
0.00

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article

Effect of N‐Acetylcysteine, Ascorbic Acid, and a Vitamin E Analog on Oxidative and Storage Lesions in Canine Packed Red Blood Cells

Andrea Pires dos Santos, Janet L. Roque‐Torres, Priscila B. S. Serpa, Andrew D. Woolcock et al.
Journal of Veterinary Emergency and Critical Care
Heme Oxygenase-1 and Carbon Monoxide
article

Effect of N‐Acetylcysteine, Ascorbic Acid, and a Vitamin E Analog on Oxidative and Storage Lesions in Canine Packed Red Blood Cells

Andrea Pires dos Santos, Janet L. Roque‐Torres, Priscila B. S. Serpa, Andrew D. Woolcock, George E. Moore, Abhijit Mukhopadhyay
article en

Abstract

The addition of AA and a VE to canine pRBCs reduced ROS accumulation but did not prevent glutathione depletion during routine storage. Further studies using antioxidants as additives in canine pRBCs are warranted.

Journal of Veterinary Emergency and Critical CareVol. 35(3)
Purdue University West Lafayette (US), Virginia Tech (US)
Purdue University, American College of Veterinary Internal Medicine
Openalex Percentile: Top 85%
Heme Oxygenase-1 and Carbon Monoxide
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