Drug Repurposing Targeting miRNA-mRNA Networks to Mitigate Areca Nut-Induced Head and Neck Cancer
This integrative approach elucidates areca nut-driven carcinogenesis through miRNA-mRNA interactions and highlights MK-2206 as a promising therapeutic strategy for areca nut-associated HNC.
Authors
- Hung-Han Huang (ORCID: https://orcid.org/0009-0007-9161-1323)
- Guo-Rung You
- Joseph Tung‐Chieh Chang (ORCID: https://orcid.org/0000-0003-4227-0546)
- Ching‐Chi Chiu (ORCID: https://orcid.org/0000-0002-1827-8049)
- Eric Yi-Liang Shen (ORCID: https://orcid.org/0000-0003-2910-1393)
- Yi‐Fang Huang (ORCID: https://orcid.org/0000-0003-2569-999X)
- Ann‐Joy Cheng (ORCID: https://orcid.org/0000-0002-1317-0725)
- Yi‐Chen Li (ORCID: https://orcid.org/0000-0002-5103-7642)
- Yu-Chen Huang
- Yin-Ju Chen
Institutions
- Chang Gung University of Science and Technology (TW)
- Chang Gung University (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- National Cheng Kung University Hospital (TW)
Publication Details
- Journal
- Biomedical Journal
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1016/j.bj.2025.100886
- Citations
- 5
- Primary Topic
- Oral Health Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 7.33
Funders
- Chang Gung Memorial Hospital