A Causal Inference Study of Circulating Metabolites Mediating the Effect of Obesity‐Related Indicators on the Incidence of Anxiety Disorders

This study establishes a significant causal relationship between obesity and anxiety, with three circulating metabolites playing a clear mediating role. Thus, targeting these metabolites could significantly reduce the burden of AD associated with obesity.

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Publication Details

Journal
Brain and Behavior
Published
2025-07-01
DOI
https://doi.org/10.1002/brb3.70653
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

A Causal Inference Study of Circulating Metabolites Mediating the Effect of Obesity‐Related Indicators on the Incidence of Anxiety Disorders

Wenlin Gai, Cheng Qin
Brain and Behavior
Genetic Associations and Epidemiology
article

A Causal Inference Study of Circulating Metabolites Mediating the Effect of Obesity‐Related Indicators on the Incidence of Anxiety Disorders

Wenlin Gai, Cheng Qin
article en

Abstract

This study establishes a significant causal relationship between obesity and anxiety, with three circulating metabolites playing a clear mediating role. Thus, targeting these metabolites could significantly reduce the burden of AD associated with obesity.

Brain and BehaviorVol. 15(7)
Beijing Institute of Education (CN), Xijing Hospital (CN), Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences, Air Force Medical University (CN)
Good health and well-being
Openalex Percentile: Top 81%
Genetic Associations and Epidemiology
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