Hemorrhagic Fever with Renal Syndrome: Current State of the Issue in the Russian Federation and Assessment of Epidemiological Risks for 2025

The results of epizootiological and epidemiological monitoring of hemorrhagic fever with renal syndrome (HFRS) in the Russian Federation in 2024 and a forecast for 2025 are presented in the paper. In 2024, 3,396 cases of HFRS were registered in the Russian Federation (3.32 per 100 thousand population) – a decrease in the incidence of HFRS by 32.3 % as compared to previous year’s data was noted. The age structure of the patients was dominated by people aged 30–59 years (66.3 %, with some exceptions); 161 cases of the disease were observed among children under 17 years of age. The share of the male population was 72 %. The mortality rate was recorded at the level of 0.29 % – 10 lethal outcomes. In 2025, it is predicted that the tense epidemiological situation on HFRS will be retained in the constituent entities of the Volga and Central Federal Districts. Conditions for the occurrence of sporadic cases of HFRS will remain in the Northwestern, Ural, and Far Eastern Districts. Sporadic cases of the disease are possible in certain territories of the entities of the Southern, North Caucasian and Siberian Federal Districts. Proposals have been formulated to minimize possible epidemiological complications in the country for the forecasted period and the near future. The main areas of scientific developments aimed at improving the quality of epidemiological surveillance of HFRS, currently carried out using highly productive advanced technologies for data processing, analysis and visualization, are considered.