Comparison between Sporadic Primary Hyperparathyroidism and Multiple Endocrine Neoplasia Associated Primary Hyperparathyroidism: Retrospective Analysis of Indian PHPT Registry

Introduction: Despite heterogeneity, the most consistent presentation of multiple endocrine neoplasia (MEN) is primary hyperparathyroidism (PHPT) seen in almost 100% of cases in MEN-1 and nearly 30% in MEN-2A.This retrospective study was planned to compare the demography, clinical manifestations, management, and outcome of sporadic PHPT (s-PHPT) and multiple endocrine neoplasia (m-PHPT) patients. Methodology:This was a registry-based (www.indianphptregistry.com) retrospective cohort study from a tertiary care hospital in North India.In this study, medical records, and clinical data of s-PHPT patients and genetically proven and clinically suspected m-PHPT patients were analyzed.