Efficacy and safety of sacubitril/valsartan in Afro-descendant patients with resistant hypertension: a randomized controlled trial
Sac-Val was more effective than standard therapy in achieving BP control and reducing BP in resistant hypertension, with a dose-dependent trend favoring the 400 mg regimen. These findings support Sac-Val as a potential treatment alternative for high-risk Afro-descendant patients.
Authors
- Yasmin de Souza Lima Bitar (ORCID: https://orcid.org/0000-0003-0125-2261)
- Leonor Maria Pacheco Santos (ORCID: https://orcid.org/0000-0002-6739-6260)
- André Rodrigues Durães (ORCID: https://orcid.org/0000-0002-1506-0327)
- Marcela Gordilho Aras (ORCID: https://orcid.org/0000-0002-0939-1015)
- Eugénia Santos (ORCID: https://orcid.org/0000-0002-1895-3737)
- Edimar Alcides Bocchi (ORCID: https://orcid.org/0000-0001-9204-485X)
- Roque Aras (ORCID: https://orcid.org/0000-0002-2161-3696)
- Wallace André Pedro da Silva
- Cristiano Macedo (ORCID: https://orcid.org/0000-0003-3745-0753)
- Rodrigo Martins Abreu (ORCID: https://orcid.org/0000-0001-5819-8038)
Institutions
- Universidade Federal da Bahia (BR)
- Universidade de São Paulo (BR)
- Complexo Hospitalar Universitário Professor Edgard Santos (BR)
- Universidade do Tocantins (BR)
- Hospital Roberto del Rio (CL)
Publication Details
- Journal
- Journal of Hypertension
- Published
- 2025-07-04
- DOI
- https://doi.org/10.1097/hjh.0000000000004075
- Citations
- 1
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.39