Polydopamine Nanoparticle-Integrated Smart Bletilla striata Polysaccharide Hydrogel: Photothermal-Triggered CO2 Release for Diabetic Wound Microenvironment Modulation
The self-assembled cross-linked carboxymethyl <i>Bletilla striata</i> polysaccharide Hydrogel with CO<sub>2</sub>@PDA NPs prepared in this study has a good photothermal conversion effect. It improves the microenvironment of diabetes wounds by improving hypoxia, antibacterial, antioxidant, and other effects, providing a good multi-functional alternative material for the treatment of refractory diabetes wounds.
Authors
- Xiaojing Huang
- Zihao Ma
- Kaijun Gou
- Huan Gu (ORCID: https://orcid.org/0000-0001-7300-6997)
- Ming Zhao (ORCID: https://orcid.org/0000-0002-5801-5593)
- Qian Peng (ORCID: https://orcid.org/0000-0001-8975-8413)
- Lei Lei (ORCID: https://orcid.org/0000-0001-8430-1246)
- Yu He (ORCID: https://orcid.org/0000-0001-7434-5309)
- Xiao Wang (ORCID: https://orcid.org/0000-0002-2973-8215)
- Ying Sun (ORCID: https://orcid.org/0009-0006-2374-8566)
- Rui Zeng (ORCID: https://orcid.org/0000-0003-3971-7415)
Institutions
- Chengdu Sport University (CN)
- Sichuan Academy of Traditional Chinese Medicine (CN)
- Southwest Minzu University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/ijn.s525172
- Citations
- 4
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.10