The role of inorganic compounds in pharmaceutical preparations: an example of quality control of sodium selenite in the product “Devivit Selenium”
The article examines an example of the practical application of knowledge of inorganic chemistry in the pharmaceutical industry through the analysis of the veterinary medicinal product “Devivit Selenium”, which contains selenium in the form of sodium selenite. Selenium is a vital trace element, the biological activity of which largely depends on the chemical form. The need to control the qualitative and quantitative composition of selenium-containing drugs in order to ensure their safety and effectiveness is substantiated. The main attention is paid to the development of a method for determining selenium content by redox titration using iodine, sodium thiosulfate, potassium iodide and starch indicator. The hardware, the procedure for preparing solutions and the analysis algorithm are described in detail. The results obtained demonstrate that the proposed method is accurate, reliable and suitable for routine laboratory use. The level of sodium selenite established in the drug samples meets the quality standards, which confirms the reliability of the method. The study has not only practical but also pedagogical significance: it can be used as a teaching example to consolidate knowledge in redox chemistry, chemical analysis and pharmaceutical control. The materials of the work are also the basis for developing students' skills in drug analysis, critical thinking and professional responsibility in the field of chemistry, pharmacy and veterinary medicine.
Authors
- B. V. Gutyj (ORCID: https://orcid.org/0000-0002-5971-8776)
- T. A. Velesyk (ORCID: https://orcid.org/0000-0003-3201-9323)
- О. А. Кацараба (ORCID: https://orcid.org/0000-0001-8520-224X)
- Р. М. Сачук (ORCID: https://orcid.org/0000-0003-4532-4220)
- I. V. Vyhovskyi
Institutions
- Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv (UA)
- Rivne State University of Humanities (UA)
Publication Details
- Journal
- Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies
- Published
- 2025-03-01
- DOI
- https://doi.org/10.32718/nvlvet-a10231
- Citations
- 2
- Primary Topic
- Chemical Thermodynamics and Molecular Structure
- Type
- article
- Field-Weighted Citation Impact
- 1.87