Impending myxedema as a manifestation of subclinical hypothyroidism in a case of systemic lupus erythematosus: A case report

This case, one of only 6 reported instances of myxedema coma occurring in subclinical hypothyroidism, underscores that this life-threatening condition can develop even without classic hypothyroid features, particularly amidst significant physiological stressors like sepsis and SLE. A high index of suspicion, prompt diagnosis based on biochemical findings, and immediate initiation of thyroid hormone replacement are critical for successful management.

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Publication Details

Journal
Medicine
Published
2025-07-04
DOI
https://doi.org/10.1097/md.0000000000042892
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Impending myxedema as a manifestation of subclinical hypothyroidism in a case of systemic lupus erythematosus: A case report

Ermias Habte Gebremichael, Tamirat Godebo Woyimo
Medicine
Thyroid Disorders and Treatments
article

Impending myxedema as a manifestation of subclinical hypothyroidism in a case of systemic lupus erythematosus: A case report

Ermias Habte Gebremichael, Tamirat Godebo Woyimo
article en

Abstract

This case, one of only 6 reported instances of myxedema coma occurring in subclinical hypothyroidism, underscores that this life-threatening condition can develop even without classic hypothyroid features, particularly amidst significant physiological stressors like sepsis and SLE. A high index of suspicion, prompt diagnosis based on biochemical findings, and immediate initiation of thyroid hormone replacement are critical for successful management.

MedicineVol. 104(27)
Jimma University (ET)
Good health and well-being
Openalex Percentile: Top 76%
Thyroid Disorders and Treatments
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