Crescentic glomerulonephritis associated with NK-large granular lymphocytic leukemia: A case report

In short, we report a unique case diagnosed with crescentic glomerulonephritis associated with NK-LGLL, with pathogenic N642H mutation in STAT5B, Epstein-Barr virus infection and poor prognosis, different from typical inert type. Close monitoring of renal function is suggested for similar NK-LGLL patients.

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Publication Details

Journal
Medicine
Published
2025-07-04
DOI
https://doi.org/10.1097/md.0000000000043294
Primary Topic
Chronic Lymphocytic Leukemia Research
Type
article
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Crescentic glomerulonephritis associated with NK-large granular lymphocytic leukemia: A case report

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Crescentic glomerulonephritis associated with NK-large granular lymphocytic leukemia: A case report

Ze Wu, Rong Tang, Xiang Ao, Zefeng Wang, Wei Lin, Jianxia Tang, Ting Meng, Zengyuan Luo
article en

Abstract

In short, we report a unique case diagnosed with crescentic glomerulonephritis associated with NK-LGLL, with pathogenic N642H mutation in STAT5B, Epstein-Barr virus infection and poor prognosis, different from typical inert type. Close monitoring of renal function is suggested for similar NK-LGLL patients.

MedicineVol. 104(27)
Central South University (CN), Xiangya Hospital Central South University (CN)
Good health and well-being
Openalex Percentile: Top 77%
Chronic Lymphocytic Leukemia Research
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