Pluronic P123/L64 Mixed Micelles as Immediate Release Systems to Enhance the Bioavailability of Praziquantel in Rats
The findings of this study confirm that Pluronic P123/L64 PMMs represent a novel and promising approach for enhancing solubility and bioavailability of PZQ, both in vitro and in vivo. The development of immediate release formulations is anticipated to be an effective option for drugs exhibiting a notable first-pass effect.
Authors
- Jing Yuan (ORCID: https://orcid.org/0000-0002-8937-9568)
- Tong Jia (ORCID: https://orcid.org/0009-0004-8152-8663)
- Jie Gao (ORCID: https://orcid.org/0000-0003-2021-819X)
- Xiaoqing Ma (ORCID: https://orcid.org/0009-0008-0128-9703)
- Ronghuan Yin (ORCID: https://orcid.org/0000-0001-5021-0274)
- Wenhao Su
Institutions
- Shenyang Agricultural University (CN)
- Ministry of Agriculture and Rural Affairs (CN)
- Northeastern University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/ijn.s520910
- Citations
- 1
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.79
Funders
- Shenyang Agricultural University