Predictors of Clinical Stability and Mortality in COPD: A Longitudinal Study
Our study identified several predictors of 2-year clinical stability in patients with COPD. However, clinical stability at 2 years did not predict subsequent mortality. These findings suggest that clinical stability and mortality are distinct outcomes that are driven by different sets of predictive variables. This underscores the need for a comprehensive approach to COPD management that not only addresses exacerbations and symptoms, but also considers a broader range of factors influencing survival, particularly the management of comorbidities such as cardiovascular disease.
Authors
- Mariko Siyue Koh (ORCID: https://orcid.org/0000-0002-1230-0129)
- Pei Yee Tiew (ORCID: https://orcid.org/0000-0002-6346-2072)
- Wesley Teck Wee Loo (ORCID: https://orcid.org/0009-0003-7466-8302)
- Therese Sophie Lapperre (ORCID: https://orcid.org/0000-0002-5176-0101)
- Jessica Tan
- Si Yuan Chew (ORCID: https://orcid.org/0000-0002-5098-9596)
- Rui Ya Soh
Institutions
- University of Antwerp (BE)
- Nanyang Technological University (SG)
- Singapore General Hospital (SG)
- Antwerp University Hospital (BE)
- Duke-NUS Medical School (SG)
- Sengkang General Hospital (SG)
Publication Details
- Journal
- International Journal of COPD
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/copd.s531435
- Citations
- 3
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- National Research Foundation
- National Research Foundation Singapore
- Medical Research Council
- National Medical Research Council