The Evolving Global Burden of Young‐Onset Parkinson's Disease (1990–2021): Regional, Gender, and Age Disparities in the Context of Rising Incidence and Declining Mortality
YOPD disproportionately impacts working-age populations, with geographic, gender, and age disparities. This analysis establishes YOPD as a priority condition for global neurological health initiatives, particularly in middle SDI regions and Asia, requiring differentiated regional approaches to mitigate its growing impact on working-age populations.
Authors
- Xingyi He (ORCID: https://orcid.org/0000-0003-4223-0800)
- Shipeng Zhang (ORCID: https://orcid.org/0000-0002-9462-2841)
- Xiaoyu Zhu (ORCID: https://orcid.org/0000-0003-3333-689X)
- Qinwei Fu (ORCID: https://orcid.org/0000-0002-2383-9146)
- Xinlang Yu
- Yan Lu (ORCID: https://orcid.org/0000-0002-7986-2599)
- Zhihui Jin
- Wenshan Li (ORCID: https://orcid.org/0000-0002-7968-2678)
- Rui Fu (ORCID: https://orcid.org/0000-0001-7969-4970)
- Hanyu Wang (ORCID: https://orcid.org/0000-0001-9909-2029)
- Yanjie Jiang
Institutions
- Nanjing University of Chinese Medicine (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
- Impact (CA)
- Chengdu University of Traditional Chinese Medicine (CN)
- McMaster University (CA)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1002/brb3.70659
- Citations
- 3
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.17
Funders
- National Natural Science Foundation of China