Assessment of hip and femur fractures in patients with chronic kidney disease: A clinical evaluation

Introduction: Chronic kidney disease (CKD) is a progressive condition characterized by declining kidney function, which also impacts bone metabolism, particularly through vitamin D activation. Patients with CKD are at an increased risk of osteoporosis and delayed bone healing. This study aims to evaluate the relationship between CKD and clinical outcomes in patients with hip and femur fractures. Materials and Methods: Serum creatinine and urea levels, along with RUSH and BMD scores, were analyzed in patients. Statistical analysis was performed to assess the correlation between these variables. Results: Higher serum urea and creatinine levels were associated with lower BMD and RUSH scores, indicating poorer bone density and delayed healing. However, the correlation was weak. Conclusion: Although kidney function markers such as creatinine and urea suggest a potential link with fracture healing outcomes, the relationship remains weak. Continuous monitoring of kidney function is essential in hospitalized patients, but further research with a larger sample size and comprehensive monitoring is needed to better understand fracture recovery in CKD patients.

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Publication Details

Journal
Journal of Medical and Scientific Research
Published
2025-04-02
DOI
https://doi.org/10.17727/jmsr.2024/13-36
Primary Topic
Bone and Joint Diseases
Type
article
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article

Assessment of hip and femur fractures in patients with chronic kidney disease: A clinical evaluation

Kandavel Shanmugam, K Vellingiri, Suryanarayana MSA, Rasquinha CJ et al.
Journal of Medical and Scientific Research
Bone and Joint Diseases
article

Assessment of hip and femur fractures in patients with chronic kidney disease: A clinical evaluation

Kandavel Shanmugam, K Vellingiri, Suryanarayana MSA, Rasquinha CJ, B Sreeharin
article en

Abstract

Introduction: Chronic kidney disease (CKD) is a progressive condition characterized by declining kidney function, which also impacts bone metabolism, particularly through vitamin D activation. Patients with CKD are at an increased risk of osteoporosis and delayed bone healing. This study aims to evaluate the relationship between CKD and clinical outcomes in patients with hip and femur fractures. Materials and Methods: Serum creatinine and urea levels, along with RUSH and BMD scores, were analyzed in patients. Statistical analysis was performed to assess the correlation between these variables. Results: Higher serum urea and creatinine levels were associated with lower BMD and RUSH scores, indicating poorer bone density and delayed healing. However, the correlation was weak. Conclusion: Although kidney function markers such as creatinine and urea suggest a potential link with fracture healing outcomes, the relationship remains weak. Continuous monitoring of kidney function is essential in hospitalized patients, but further research with a larger sample size and comprehensive monitoring is needed to better understand fracture recovery in CKD patients.

Journal of Medical and Scientific ResearchVol. 13(2)
Openalex Percentile: Top 79%
Bone and Joint Diseases
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