Mechanism of SiMiaoWan in the Treatment of Hyperuricemia Based on Serum Metabolomics
SMW effectively reduced the SUA level in hyperuricemic rat models and alleviated the renal impairment induced by hyperuricemia. The mechanism of SMW is closely associated with pathways related to central carbon metabolism in cancer, protein digestion and absorption, and amino acid biosynthesis.
Authors
- Xiangjun Qiu (ORCID: https://orcid.org/0000-0002-7644-9598)
- Mengping Guo
- Xiaochen Ding
- Xiuzhen Wang (ORCID: https://orcid.org/0000-0002-1548-4525)
- Bo Sun (ORCID: https://orcid.org/0000-0002-6132-3765)
- Jingxiang Su
Institutions
- Henan University of Science and Technology (CN)
- Luoyang Orthopedic-Traumatological Hospital of Henan Province (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/dddt.s533394
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00