Serum Uric Acid-to-Serum Creatinine Ratio, Thyroid Function, and Gestational Diabetes Mellitus Risk during Early Pregnancy among Chinese Women
Both UA:SCr ratio and FT<sub>4</sub> were associated with the risk of GDM in early pregnancy, particularly among women in the highest prepregnancy BMI quartile. FT<sub>4</sub> level within the normal range was correlated with UA:SCr ratio in women in the third and fourth prepregnancy BMI quartiles. These results suggest the complex interplay of metabolic changes during early pregnancy and provide new insights for the early prevention and management of GDM.
Authors
- Yanbei Duo (ORCID: https://orcid.org/0000-0002-9867-9087)
- Tao Yuan (ORCID: https://orcid.org/0000-0003-1966-0829)
- Weigang Zhao (ORCID: https://orcid.org/0000-0002-2797-2614)
- Yong Fu (ORCID: https://orcid.org/0000-0001-6480-1147)
- Yuemei Zhang (ORCID: https://orcid.org/0000-0003-3555-4524)
- Yan Chen (ORCID: https://orcid.org/0009-0000-4929-0641)
- Shuoning Song (ORCID: https://orcid.org/0000-0003-4810-4063)
- Yingyue Dong
- Xiaoli Qiao
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Hainan Maternal and Child Health Hospital (CN)
- Beijing Chaoyang Emergency Medical Center (CN)
Publication Details
- Journal
- Diabetes Metabolic Syndrome and Obesity
- Published
- 2025-07-01
- DOI
- https://doi.org/10.2147/dmso.s486695
- Citations
- 2
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- National Science and Technology Major Project