Hypoxia‐Inducible Factor HIF1α Regulates the Expression of SLC7A1 to Mediate Erastin‐Induced Ferroptosis in Cervical Cancer Cells

HIF1α regulates the expression of YTHDF1, thereby enhancing the m6A modification level of SLC7A1, promoting its expression, and ultimately inhibiting Erastin-induced ferroptosis in CaCx cells.

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Publication Details

Journal
The Journal of Gene Medicine
Published
2025-07-01
DOI
https://doi.org/10.1002/jgm.70027
Citations
1
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
0.81
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article

Hypoxia‐Inducible Factor HIF1α Regulates the Expression of SLC7A1 to Mediate Erastin‐Induced Ferroptosis in Cervical Cancer Cells

Yan Lei, Yanling Li, Yanqing Huang
1 citations
The Journal of Gene Medicine
RNA modifications and cancer
0.81
article

Hypoxia‐Inducible Factor HIF1α Regulates the Expression of SLC7A1 to Mediate Erastin‐Induced Ferroptosis in Cervical Cancer Cells

Yan Lei, Yanling Li, Yanqing Huang
article en
1 citations

Abstract

HIF1α regulates the expression of YTHDF1, thereby enhancing the m6A modification level of SLC7A1, promoting its expression, and ultimately inhibiting Erastin-induced ferroptosis in CaCx cells.

The Journal of Gene MedicineVol. 27(7)
Central South University (CN), Hunan Cancer Hospital (CN)
Openalex Percentile: Top 26%
RNA modifications and cancer
0.81
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