Exploring Long Noncoding RNAs and Ferroptosis in Cancer Progression
Ferroptosis is a new type of regulated cell death produced by iron-dependent accumulation of reactive oxygen species in lipids, which is different from apoptosis, pyroptosis and autophagy, and plays the role of a "double-edged sword" in tumor therapy. Ferroptosis-related lncRNA are involved in tumor cell death by regulating lipid metabolism and ferroptosis-associated genes, thus becoming one of the hotspots in the field of tumor-targeted therapy. In this paper, we review the role of ferroptosis and its related lncRNA in inhibiting the development of tumor cells and improving the therapeutic effect of drugs, which is expected to provide a new strategy for the treatment of tumors.
Authors
- Liang Yan (ORCID: https://orcid.org/0000-0001-9066-8693)
- Q. Mo
- Wenbo Pang (ORCID: https://orcid.org/0000-0002-6685-3730)
- Wei Qin (ORCID: https://orcid.org/0000-0003-2161-387X)
- Yan Qiu (ORCID: https://orcid.org/0000-0001-6691-2828)
- Xuefei Fan (ORCID: https://orcid.org/0009-0006-9277-0214)
Institutions
- Guangxi Medical University (CN)
- The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine (CN)
- Heilongjiang Center for Tuberculosis Control and Prevention (CN)
- Regional Center for Prevention and Control of AIDS and Infectious Diseases (RU)
- The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
Publication Details
- Journal
- Life Conflux
- Published
- 2025-03-30
- DOI
- https://doi.org/10.71321/jjrzya36
- Citations
- 10
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 9.36