Severe dengue encephalitis showcasing the “double doughnut sign” on MRI: A case report
Severe dengue can lead to fatal complications, including dengue encephalitis. We report a 14-year-old girl with severe dengue who presented with bilateral thalamic hemorrhagic infarction, indicated by distinct brain imaging findings (the so-called "double doughnut sign"), which is a rare presentation of a common infection. Positive dengue antigen and IgM tests were noted. The patient required critical care, including intubation and resuscitation, but was discharged improved and continues follow-up at our neurology clinic. This case highlights that dengue infection can be complicated by meningoencephalitis, and a high index of suspicion is needed to diagnose our patients promptly. Furthermore, imaging modalities such as MRI play a key role in diagnosing and managing patients with dengue encephalitis.
Authors
- China Tolessa Sedi (ORCID: https://orcid.org/0000-0001-7644-0801)
- Salhadin Mohammed (ORCID: https://orcid.org/0000-0003-1016-9486)
- A. Mustafa (ORCID: https://orcid.org/0000-0003-0032-8834)
- Surafel Tilahun Maru (ORCID: https://orcid.org/0000-0002-3432-5466)
- Aman Edao Bime (ORCID: https://orcid.org/0009-0004-4771-3574)
- Hussen Nuri Saliha
Institutions
- Haramaya University (ET)
- Wollo University (ET)
- Addis Ababa University (ET)
- University of Gondar (ET)
Publication Details
- Journal
- Radiology Case Reports
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1016/j.radcr.2025.06.043
- Citations
- 1
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 1.88