Severe dengue encephalitis showcasing the “double doughnut sign” on MRI: A case report

Severe dengue can lead to fatal complications, including dengue encephalitis. We report a 14-year-old girl with severe dengue who presented with bilateral thalamic hemorrhagic infarction, indicated by distinct brain imaging findings (the so-called "double doughnut sign"), which is a rare presentation of a common infection. Positive dengue antigen and IgM tests were noted. The patient required critical care, including intubation and resuscitation, but was discharged improved and continues follow-up at our neurology clinic. This case highlights that dengue infection can be complicated by meningoencephalitis, and a high index of suspicion is needed to diagnose our patients promptly. Furthermore, imaging modalities such as MRI play a key role in diagnosing and managing patients with dengue encephalitis.

Authors

Institutions

Publication Details

Journal
Radiology Case Reports
Published
2025-07-05
DOI
https://doi.org/10.1016/j.radcr.2025.06.043
Citations
1
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
1.88
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Severe dengue encephalitis showcasing the “double doughnut sign” on MRI: A case report

China Tolessa Sedi, Salhadin Mohammed, A. Mustafa, Surafel Tilahun Maru et al.
1 citations
Radiology Case Reports
Mosquito-borne diseases and control
1.88
article

Severe dengue encephalitis showcasing the “double doughnut sign” on MRI: A case report

China Tolessa Sedi, Salhadin Mohammed, A. Mustafa, Surafel Tilahun Maru, Aman Edao Bime, Hussen Nuri Saliha
article en
1 citations

Abstract

Severe dengue can lead to fatal complications, including dengue encephalitis. We report a 14-year-old girl with severe dengue who presented with bilateral thalamic hemorrhagic infarction, indicated by distinct brain imaging findings (the so-called "double doughnut sign"), which is a rare presentation of a common infection. Positive dengue antigen and IgM tests were noted. The patient required critical care, including intubation and resuscitation, but was discharged improved and continues follow-up at our neurology clinic. This case highlights that dengue infection can be complicated by meningoencephalitis, and a high index of suspicion is needed to diagnose our patients promptly. Furthermore, imaging modalities such as MRI play a key role in diagnosing and managing patients with dengue encephalitis.

Radiology Case ReportsVol. 20(9)
Haramaya University (ET), Wollo University (ET), Addis Ababa University (ET), University of Gondar (ET)
Zero hunger
Openalex Percentile: Top 14%
Mosquito-borne diseases and control
1.88
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.