Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report

Radiofrequency ablation (RFA) plays a crucial role in the treatment of benign thyroid nodules by offering a minimally invasive alternative to surgical interventions. Nodule rupture is an uncommon complication of RFA. We present a case of nodule rupture and hyperthyroidism after RFA 41 days in a 45-year-old male patient. The neck ultrasound revealed the disruption of the thyroid nodule capsule and a mass adjacent to the thyroid nodule. Thyroid function tests suggested of hyperthyroidism. The patient was received conservative treatment. Follow-up, the biochemical tests showed TSH and FT4 returned to normal limits 2 weeks later. Five months after radiofrequency ablation shows the thyroid nodule was decrease 92% volume compared to the volume immediately postablation and the soft tissue lesion in the right neck region was completely regressed.

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Publication Details

Journal
Radiology Case Reports
Published
2025-07-05
DOI
https://doi.org/10.1016/j.radcr.2025.06.020
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report

Le Thi My, Ngo Van Doan, Nguyen Thi Thu Hien, Cuong Duy et al.
Radiology Case Reports
Thyroid Cancer Diagnosis and Treatment
article

Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report

Le Thi My, Ngo Van Doan, Nguyen Thi Thu Hien, Cuong Duy, Thieu‐Thi Tra My, Tran Thi Hoang Anh, Ngo Thi Thanh Tu, Pham Vu Hiep, Vu Mai Quynh
article en

Abstract

Radiofrequency ablation (RFA) plays a crucial role in the treatment of benign thyroid nodules by offering a minimally invasive alternative to surgical interventions. Nodule rupture is an uncommon complication of RFA. We present a case of nodule rupture and hyperthyroidism after RFA 41 days in a 45-year-old male patient. The neck ultrasound revealed the disruption of the thyroid nodule capsule and a mass adjacent to the thyroid nodule. Thyroid function tests suggested of hyperthyroidism. The patient was received conservative treatment. Follow-up, the biochemical tests showed TSH and FT4 returned to normal limits 2 weeks later. Five months after radiofrequency ablation shows the thyroid nodule was decrease 92% volume compared to the volume immediately postablation and the soft tissue lesion in the right neck region was completely regressed.

Radiology Case ReportsVol. 20(9)
Vinmec Times City International Hospital (VN), VinUniversity (VN)
Openalex Percentile: Top 76%
Thyroid Cancer Diagnosis and Treatment
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