Granular Cell Tumours of the Breast: A Case Series and Literature Review

Granular cell tumours (GCTs) are rare tumours that can occur in any part of the body but are commonly observed in the skin, digestive tract, and subcutaneous tissues, with the oral cavity being the most common anatomical location. Breast involvement has been reported in a small proportion of cases and is commonly benign. However, some of these lesions can be malignant. In this study, two cases of benign granular breast cell tumours in women aged 31 and 39 years are highlighted and discussed. This study shows similarities between the clinical and radiological presentation of GCTs with breast malignancies and the associated management difficulties that can be encountered.

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Publication Details

Journal
Cureus
Published
2025-07-05
DOI
https://doi.org/10.7759/cureus.87336
Primary Topic
Tumors and Oncological Cases
Type
article
Field-Weighted Citation Impact
0.00
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article

Granular Cell Tumours of the Breast: A Case Series and Literature Review

Lester Chee Hao Leong, Cheryl Hui Shan Lim, Ying Ching Tan, Chow Yin Wong et al.
Cureus
Tumors and Oncological Cases
article

Granular Cell Tumours of the Breast: A Case Series and Literature Review

Lester Chee Hao Leong, Cheryl Hui Shan Lim, Ying Ching Tan, Chow Yin Wong, Sofeah Samsuddin
article en

Abstract

Granular cell tumours (GCTs) are rare tumours that can occur in any part of the body but are commonly observed in the skin, digestive tract, and subcutaneous tissues, with the oral cavity being the most common anatomical location. Breast involvement has been reported in a small proportion of cases and is commonly benign. However, some of these lesions can be malignant. In this study, two cases of benign granular breast cell tumours in women aged 31 and 39 years are highlighted and discussed. This study shows similarities between the clinical and radiological presentation of GCTs with breast malignancies and the associated management difficulties that can be encountered.

CureusVol. 17(7)
Singapore General Hospital (SG), SingHealth Duke-NUS Academic Medical Centre (SG), National Cancer Centre Singapore (SG)
Gender equality
Openalex Percentile: Top 76%
Tumors and Oncological Cases
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