Comparative Assessment of Chemotherapy Followed by Consolidative Radical Cystectomy Versus Chemoradiation for Clinically Node-Positive Urothelial Carcinoma of the Bladder

Patients with cN+ bladder cancer who received CRT had a worse prognosis compared to those who underwent chemotherapy followed by RC. The incorporation of more effective systemic therapies is required to improve outcomes, as in our analysis, only one in four cN+ patients survived beyond 5 years.

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Publication Details

Journal
Clinical Genitourinary Cancer
Published
2025-07-05
DOI
https://doi.org/10.1016/j.clgc.2025.102399
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparative Assessment of Chemotherapy Followed by Consolidative Radical Cystectomy Versus Chemoradiation for Clinically Node-Positive Urothelial Carcinoma of the Bladder

Paweł Rajwa, Roberto Contieri, Pietro Scilipoti, Aleksander Ślusarczyk et al.
Clinical Genitourinary Cancer
Bladder and Urothelial Cancer Treatments
article

Comparative Assessment of Chemotherapy Followed by Consolidative Radical Cystectomy Versus Chemoradiation for Clinically Node-Positive Urothelial Carcinoma of the Bladder

Paweł Rajwa, Roberto Contieri, Pietro Scilipoti, Aleksander Ślusarczyk, Mattia Longoni, Wojciech Krajewski, Andrea Gallioli, Marco Moschini, Paras Shah, Marcin Miszczyk, Mario de Angelis, Ekaterina Laukhtina, Stephen A. Boorjian, Benjamin Pradere, Piotr Radziszewski, Francesco Del Giudice
article en

Abstract

Patients with cN+ bladder cancer who received CRT had a worse prognosis compared to those who underwent chemotherapy followed by RC. The incorporation of more effective systemic therapies is required to improve outcomes, as in our analysis, only one in four cN+ patients survived beyond 5 years.

Clinical Genitourinary CancerVol. 23(5)
Universitat Autònoma de Barcelona (ES), Medical University of Warsaw (PL), Policlinico Umberto I (IT), Wroclaw Medical University (PL), Comprehensive Cancer Center Vienna (AT), Mayo Clinic in Arizona (US), IRCCS Ospedale San Raffaele (IT), Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT), Puigvert Foundation (ES), University College London (GB), Medical University of Vienna (AT)
Fundacja na rzecz Nauki Polskiej, European Association of Urology, Narodowa Agencja Wymiany Akademickiej, Agencja Badań Medycznych
Good health and well-being
Openalex Percentile: Top 72%
Bladder and Urothelial Cancer Treatments
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