Effective Sirolimus Use in Prenatal and Postnatal Management of Symptomatic Extensive Congenital Capillary-Lymphatic-Venous Malformations (CLVMs): A Report of Two Cases
Administration of sirolimus during pregnancy with maternal blood drug-level monitoring seems to be an efficient and safe treatment option that should be considered in high-risk fetal CLVMs.
Authors
- lek. Łukasz Matwiejczyk
- Magda Rybak-Krzyszkowska (ORCID: https://orcid.org/0000-0002-6993-8078)
- Iwona Domżalska-Popadiuk (ORCID: https://orcid.org/0000-0002-4952-6172)
- Anna Gabrych (ORCID: https://orcid.org/0000-0003-3598-4719)
- Katarzyna Wartecka-Zielińska
- Dariusz Wydra (ORCID: https://orcid.org/0000-0002-4510-9558)
- Anna Jankowska (ORCID: https://orcid.org/0000-0003-3606-8915)
- Natalia Mazur (ORCID: https://orcid.org/0000-0003-2473-3172)
- Anna Kłosowska (ORCID: https://orcid.org/0000-0002-4378-5683)
- Katarzyna Sinacka
- Dariusz Wyrzykowski (ORCID: https://orcid.org/0000-0002-3823-3286)
- Ninela Irga‐Jaworska (ORCID: https://orcid.org/0000-0002-7637-4397)
- Małgorzata Styczewska (ORCID: https://orcid.org/0000-0001-8280-1319)
- Ewa Bień (ORCID: https://orcid.org/0000-0002-2091-2686)
- Anna Taczanowska-Niemczuk (ORCID: https://orcid.org/0009-0009-7280-5557)
- Małgorzata Krawczyk (ORCID: https://orcid.org/0000-0001-7093-8975)
- Wojciech Górecki
- Przemysław Adamski (ORCID: https://orcid.org/0000-0001-8564-0784)
- Lena Gluszkiewicz
- Paulina Kielpinska
- Daria Dziechcinska-Poletek
Institutions
- Jagiellonian University (PL)
- University Clinical Centre (PL)
- Ekoinwentyka (Poland) (PL)
- Krakow Cardiovascular Research Institute (PL)
- Gdańsk Medical University (PL)
Publication Details
- Journal
- Pediatric Drugs
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1007/s40272-025-00708-3
- Citations
- 3
- Primary Topic
- Vascular Malformations and Hemangiomas
- Type
- article
- Field-Weighted Citation Impact
- 6.02