Utility of Pharmacological Agents for Diabetes Mellitus in the Prevention of Alzheimer’s Disease: Comparison of Metformin, Glucagon-Like Peptide-1 (GLP-1) Agonists, Insulin, and Sulfonylureas
Metformin, previously thought to have significant benefits in preventing neurodegeneration, may not be the optimal pharmacologic agent of choice, particularly in patients with DM, if neurodegeneration is a primary concern in treatment decision-making based on other risk factors.
Authors
- Elias Rizk (ORCID: https://orcid.org/0000-0001-6424-6091)
- Andrea Shehaj (ORCID: https://orcid.org/0009-0008-7161-4970)
- David Millar
- C.S. Tse
- Alexandra DiGiovanni
Institutions
- Penn State Milton S. Hershey Medical Center (US)
Publication Details
- Journal
- Cureus
- Published
- 2025-07-05
- DOI
- https://doi.org/10.7759/cureus.87350
- Citations
- 1
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.29