Management Strategies for Seminal Vesicle Cysts in Zinner Syndrome: Insights From Two Cases

Zinner syndrome is a rare congenital malformation that affects the male genitourinary tract, characterized by a triad of unilateral renal agenesis, seminal vesicle cysts, and ejaculatory duct obstruction, and typically presents during the third or fourth decade of life. In this report, we present two cases illustrating distinct management pathways. One patient, with mild and stable symptoms, was successfully managed with conservative observation. The second patient, following failed medical therapy, underwent a successful laparoscopic robotic-assisted vesiculectomy with significant symptom improvement. These cases highlight the clinical variability associated with Zinner syndrome and reinforce the importance of a tailored, patient-specific approach to management. They also contribute to the growing literature supporting minimally invasive surgical techniques as a safe and effective option for selected symptomatic patients with Zinner syndrome, offering favorable outcomes with reduced morbidity.