Mesenchymal Stromal Cells from Dental Tissues Demonstrate Neuronal Potential Pre- and Post-Induction
SHEDs and DPSCs show comparable neuronal marker expression profiles, suggesting similar early neuronal differentiation potential. These findings support using undifferentiated SHEDs and DPSCs in neuroregenerative strategies, offering cost-effective and safer alternatives to pre-differentiated cells.
Authors
- Agner Henrique Dorigo Hochuli (ORCID: https://orcid.org/0000-0003-2900-7655)
- Mateus de Oliveira Lisboa (ORCID: https://orcid.org/0000-0002-2811-8356)
- Letícia Fracaro (ORCID: https://orcid.org/0000-0003-3464-777X)
- Alexandra Cristina Senegaglia (ORCID: https://orcid.org/0000-0002-8052-6357)
- Joselito Getz (ORCID: https://orcid.org/0000-0002-7259-9820)
- Ana Helena Selenko (ORCID: https://orcid.org/0000-0002-7845-8199)
- M.S. Castro (ORCID: https://orcid.org/0000-0003-2129-5875)
- Paulo Roberto Slud Brofman (ORCID: https://orcid.org/0000-0001-6401-782X)
Institutions
- Pontifícia Universidade Católica do Paraná (BR)
- Hospital de Clínicas Universidade Federal do Paraná (BR)
- National Institute of Science and Technology in Regenerative Medicine (BR)
Publication Details
- Journal
- Cells Tissues Organs
- Published
- 2025-07-04
- DOI
- https://doi.org/10.1159/000547257
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico