Upregulated Claudin-18.2 Is a Poor Prognostic Indicator for Rectal Cancer Patients Undergoing Preoperative Concurrent Chemoradiotherapy

Elevated CLDN18.2 expression is associated with adverse clinical outcomes and pathological features, yet suggests a more unfavorable treatment response in rectal cancer patients undergoing CCRT, indicating its potential as a biomarker.

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Publication Details

Journal
Oncology
Published
2025-07-04
DOI
https://doi.org/10.1159/000547239
Primary Topic
Barrier Structure and Function Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Upregulated Claudin-18.2 Is a Poor Prognostic Indicator for Rectal Cancer Patients Undergoing Preoperative Concurrent Chemoradiotherapy

Ching‐Chieh Yang, Sung-Wei Lee, Yufeng Tian, Yow‐Ling Shiue et al.
Oncology
Barrier Structure and Function Studies
article

Upregulated Claudin-18.2 Is a Poor Prognostic Indicator for Rectal Cancer Patients Undergoing Preoperative Concurrent Chemoradiotherapy

Ching‐Chieh Yang, Sung-Wei Lee, Yufeng Tian, Yow‐Ling Shiue, Wan‐Shan Li, Yu‐Hsuan Kuo, Cheng‐Yi Lin, Han-Ping Hsu, Hung‐Chang Wu, Chia‐Lin Chou
article en

Abstract

Elevated CLDN18.2 expression is associated with adverse clinical outcomes and pathological features, yet suggests a more unfavorable treatment response in rectal cancer patients undergoing CCRT, indicating its potential as a biomarker.

Oncology
Chung Hwa University of Medical Technology (TW), National Sun Yat-sen University (TW), Chi Mei Medical Center (TW), Chia Nan University of Pharmacy and Science (TW)
Good health and well-being
Openalex Percentile: Top 79%
Barrier Structure and Function Studies
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