Increased Risk of Tuberculosis Disease in Lung Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy: A Retrospective Multicenter Study

Treatment with ICI in lung cancer patients was associated with a statistically significant increase in the risk of TB disease occurrence compared to conventional platinum-based chemotherapy. Therefore, particularly in patients treated with ICI therapy, prompt respiratory sample tests should be performed for early TB disease diagnosis when new lung lesions are identified. .

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Journal
Respiration
Published
2025-07-05
DOI
https://doi.org/10.1159/000547109
Citations
3
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
4.19
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Increased Risk of Tuberculosis Disease in Lung Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy: A Retrospective Multicenter Study

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3 citations
Respiration
Tuberculosis Research and Epidemiology
4.19
article

Increased Risk of Tuberculosis Disease in Lung Cancer Patients Undergoing Immune Checkpoint Inhibitor Therapy: A Retrospective Multicenter Study

Jinsoo Min, Chang-Dong Yeo, Jeong Uk Lim, Kyu Yean Kim, Ji Won Park, Seung Hoon Kim, Joon Young Choi, Hye Seon Kang, Yeonhee Park
article en
3 citations

Abstract

Treatment with ICI in lung cancer patients was associated with a statistically significant increase in the risk of TB disease occurrence compared to conventional platinum-based chemotherapy. Therefore, particularly in patients treated with ICI therapy, prompt respiratory sample tests should be performed for early TB disease diagnosis when new lung lesions are identified. .

RespirationVol. 104(11)
The Catholic University of Korea St. Vincent's Hospital (KR), The Catholic University of Korea Incheon St. Mary's Hospital (KR), The Catholic University of Korea Uijeongbu St. Mary's Hospital (KR), The Catholic University of Korea Yeouido St. Mary's Hospital (KR), The Catholic University of Korea Daejeon St. Mary's Hospital (KR), The Catholic University of Korea Bucheon St. Mary's Hospital (KR), The Catholic University of Korea Seoul St. Mary's Hospital (KR), Catholic University of Korea (KR)
Good health and well-being
Openalex Percentile: Top 6%
Tuberculosis Research and Epidemiology
4.19
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