Duodenal obstruction secondary to metastatic breast cancer

Breast cancer is the most common malignancy affecting females and is a leading cause of cancer-related mortality worldwide. The most common sites of metastatic disease are bone, liver, lung and brain, with the gastrointestinal tract less commonly implicated. Intestinal metastasis from breast cancer is rare, with vast majority of patients being asymptomatic. Diagnosis can often be delayed due to gastrointestinal symptoms perceived to be secondary to treatment rather than malignancy. Unfortunately, intestinal metastasis is associated with a poor prognosis with the median survival being 12 months. We present the case of a 53-year-old female with a diagnosed history of metastatic breast cancer who presented to our institution with nausea, vomiting and abdominal pain and was subsequently diagnosed with a small bowel obstruction secondary to duodenal metastasis after endoscopic ultrasound-guided tissue acquisition. She was managed conservatively with chemotherapy resulting in resolution of her small bowel obstruction.

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Publication Details

Journal
Journal of Cancer Research and Therapeutics
Published
2025-04-01
DOI
https://doi.org/10.4103/jcrt.jcrt_2022_24
Primary Topic
Metastasis and carcinoma case studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Duodenal obstruction secondary to metastatic breast cancer

Bong Sik Matthew Kim, Robert O’Neill, Simon Ghaly, Rachel Dear et al.
Journal of Cancer Research and Therapeutics
Metastasis and carcinoma case studies
article

Duodenal obstruction secondary to metastatic breast cancer

Bong Sik Matthew Kim, Robert O’Neill, Simon Ghaly, Rachel Dear, Andrew S Field, J. Ferguson
article en

Abstract

Breast cancer is the most common malignancy affecting females and is a leading cause of cancer-related mortality worldwide. The most common sites of metastatic disease are bone, liver, lung and brain, with the gastrointestinal tract less commonly implicated. Intestinal metastasis from breast cancer is rare, with vast majority of patients being asymptomatic. Diagnosis can often be delayed due to gastrointestinal symptoms perceived to be secondary to treatment rather than malignancy. Unfortunately, intestinal metastasis is associated with a poor prognosis with the median survival being 12 months. We present the case of a 53-year-old female with a diagnosed history of metastatic breast cancer who presented to our institution with nausea, vomiting and abdominal pain and was subsequently diagnosed with a small bowel obstruction secondary to duodenal metastasis after endoscopic ultrasound-guided tissue acquisition. She was managed conservatively with chemotherapy resulting in resolution of her small bowel obstruction.

Journal of Cancer Research and TherapeuticsVol. 21(3)
UNSW Sydney (AU), St Vincent's Hospital Melbourne (AU), St Vincent's Hospital Sydney (AU), St Vincent's Clinic (AU), The University of Notre Dame Australia (AU)
Good health and well-being
Openalex Percentile: Top 74%
Metastasis and carcinoma case studies
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Duodenal obstruction secondary to metastatic breast cancer — Bong Sik Matthew Kim, Robert O’Neill, et al. · Journal of Cancer Research and Therapeutics (2025) | TGRS Research Map | TGRS