From transverse myelitis to Conus Medullaris Syndrome: A pediatric case report of progressive neurological complications of Ventriculus Terminalis
• This report report details a 14-year-old girl with Transverse Myelitis progressing to Conus Medullaris Syndrome. • MRI revealed cystic dilation of the Ventriculus Terminalis, indicating a rare neurological condition. • Initial symptoms included leg pain, urinary retention, and muscle weakness, leading to hospitalization. • Treatment involved Methylprednisolone and IVIg; surgery was later required for Hammer Toe. • This report emphasizes the need for careful follow-up in patients with Ventriculus Terminalis complications. Acute idiopathic Transverse Myelitis (TM) is a rare inflammatory spinal cord disorder distinguished with sensory deficits, autonomic dysfunction, and rapid onset muscle weakness, in the absence of direct infection, autoimmune disorders, or mass lesions. Conus Medullaris Syndrome (CMS) is another rare neurological condition affecting the distal segment of the spinal cord, seen as a rare complication of persistent cystic dilation of the Ventriculus Terminalis. In this report, we document the clinical and paraclinical findings of a seronegative patient initially presenting with TM, with incidental finding of Ventriculus Terminalis in Lumbar MRI, later complicating as CMS.
Authors
- Narges Hashemi (ORCID: https://orcid.org/0000-0002-1767-7873)
- Mehran Beiraghi Toosi (ORCID: https://orcid.org/0000-0002-0569-1117)
- Farrokh Seilanian Toosi (ORCID: https://orcid.org/0000-0002-2287-0301)
- Reza Nejad Shahrokh Abadi (ORCID: https://orcid.org/0000-0003-1283-1066)
- Ahmadreza Mashreghi
- Hamid Khalesi
Institutions
- Mashhad University of Medical Sciences (IR)
- Ghaem Hospital (IR)
Publication Details
- Journal
- Brain Disorders
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1016/j.dscb.2025.100258
- Primary Topic
- Peripheral Neuropathies and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00