A stepwise approach to designing and delivering the SCHeLTI trial community-family-mother-child obesity prevention intervention
This paper describes the methods for the development and implementation of the Sino-Canadian Healthy Life Trajectories Initiative (SCHeLTI) intervention, part of a World Health Organization-supported effort to prevent childhood obesity through four international randomized controlled trials. SCHeLTI is a multi-center, cluster-randomized trial in Shanghai, supporting 4500 families from preconception through the child's fifth year. This Community-Family-Mother-Child intervention includes coordinated components such as Healthy Conversation sessions, nutrition consultations, breastfeeding support, an obesity clinic, and educational courses tailored to key reproductive and developmental stages and risk profiles. Guided by implementation science principles, SCHeLTI's development followed four main phases: 1) establishing the conceptual foundation (theoretical framework, outcomes, logic model); 2) building delivery infrastructure and engaging stakeholders in formative research; 3) finalizing the intervention design tailored to families' needs; and 4) implementing the intervention, including capacity building, adaptation, and process evaluation strategies.•A four-phase development process grounded in implementation science principles guided intervention design and delivery•Tailored components align with reproductive and developmental stages and risk profiles to support family and child needs across the life course•Stakeholder engagement and iterative adaptation ensured contextual relevance and feasibility.
Authors
- Jian Xu (ORCID: https://orcid.org/0000-0001-5727-8191)
- Janelle Zhan
- Xiao-Yu Hu
- Sonia Elizabeth Semenic (ORCID: https://orcid.org/0000-0002-5357-2016)
- Yamei Yu (ORCID: https://orcid.org/0000-0002-5151-3397)
- Yanting Wu (ORCID: https://orcid.org/0000-0002-2293-1792)
- Hong Jiang (ORCID: https://orcid.org/0000-0002-2810-8000)
- Liping Wang (ORCID: https://orcid.org/0000-0002-7765-2387)
- Olivia De-Jongh González (ORCID: https://orcid.org/0000-0003-4782-9513)
- Catherine Allard (ORCID: https://orcid.org/0000-0002-8829-4984)
- Hefeng Huang
- Fengxiu Ouyang (ORCID: https://orcid.org/0000-0001-9566-8473)
- Isabelle Marc
- Jianxia Fan (ORCID: https://orcid.org/0000-0003-3338-877X)
- Myriam Landry
- William D. Fraser (ORCID: https://orcid.org/0000-0001-9042-2415)
- Jean‐Patrice Baillargeon (ORCID: https://orcid.org/0000-0002-1336-081X)
- Claire N. Tugault-Lafleur (ORCID: https://orcid.org/0000-0002-4598-9372)
- Zhirou Chen
- Yanhui Hao (ORCID: https://orcid.org/0000-0002-4616-0152)
- Cai‐Feng Wang (ORCID: https://orcid.org/0000-0003-4667-2120)
- Luigi Bouchard (ORCID: https://orcid.org/0000-0002-7852-0722)
- Nadia Abdelouahab
- Wenguang Sun (ORCID: https://orcid.org/0000-0002-1808-8106)
- Andraea Van Hulst (ORCID: https://orcid.org/0000-0002-5743-4876)
- Lise Dubois (ORCID: https://orcid.org/0000-0001-8914-1288)
- Caroline Vaillancourt
- Louise C. Mâsse (ORCID: https://orcid.org/0000-0003-2483-8791)
- Lei Chen (ORCID: https://orcid.org/0009-0008-3811-7876)
- Han Liu (ORCID: https://orcid.org/0000-0001-5951-6413)
- Ting Li (ORCID: https://orcid.org/0000-0001-8733-4625)
- Rong Zhang (ORCID: https://orcid.org/0000-0002-6889-5571)
- Wenli Fang
- Yulai Zhou (ORCID: https://orcid.org/0000-0002-0606-6786)
- Weibin Wu (ORCID: https://orcid.org/0000-0003-3637-754X)
- Zhong Cheng Luo
- Qingqing Zhu
- Anguo Peng
- Yinan Liu (ORCID: https://orcid.org/0000-0001-6442-5794)
- Reyilai Tayier
Institutions
- Mount Sinai Hospital (CA)
- Université de Sherbrooke (CA)
- University of Ottawa (CA)
- Shanghai Jiao Tong University (CN)
- University of Toronto (CA)
- National Health and Family Planning Commission (CN)
- XinHua Hospital (CN)
- Centre Hospitalier Universitaire de Sherbrooke (CA)
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- Xian Central Hospital (CN)
- Shanghai Changning Maternity and Infant Health Hospital (CN)
- Minhang District Central Hospital (CN)
- International Peace Maternity & Child Health Hospital (CN)
- Songjiang District Central Hospital (CN)
- Lishui Maternity and Child Health Care Hospital (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- BC Children's Hospital (CA)
- Shanghai Children's Hospital (CN)
- Université Laval (CA)
- McGill University (CA)
Publication Details
- Journal
- MethodsX
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1016/j.mex.2025.103493
- Primary Topic
- Health Policy Implementation Science
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- BC Children's Hospital
- Michael Smith Health Research BC
- National Natural Science Foundation of China
- Canadian Institutes of Health Research
- Fonds de Recherche du Québec - Santé