Circulating microRNAs differentiate nociceptive and nociplastic pain: An exploratory study
This pilot study suggests that circulating miRNAs may aid in differentiating nociceptive and nociplastic pain mechanisms and tracking treatment effects. While preliminary, these findings support the potential utility of miRNA-based biomarkers in precision pain diagnostics and personalized management strategies.
Authors
- Yuichiro Toda
- Kazunori Iwasa (ORCID: https://orcid.org/0000-0001-8908-5335)
- Hiroyuki Nishie (ORCID: https://orcid.org/0000-0002-3115-3451)
- Takeshi Nagasaka (ORCID: https://orcid.org/0000-0002-4236-350X)
- Yuka Sakuta
- Hideki Nakatsuka
- Shigeru Mitani
Institutions
- Kawasaki Medical School (JP)
- Osaka City University (JP)
- Kawasaki Medical School Hospital (JP)
Publication Details
- Journal
- Neurobiology of Pain
- Published
- 2025-07-01
- DOI
- https://doi.org/10.1016/j.ynpai.2025.100191
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science London
- Japan Society for the Promotion of Science