Impact on the microstructure of deep gray matter in unvaccinated patients after moderate-to-severe COVID-19: insights from MRI T1 mapping
We hypothesized altered T1 relaxation times in deep gray matter after COVID-19. Unvaccinated participants ≥ 40 years exhibited higher striatal, hippocampal qT1 after moderate-to-severe COVID-19. No qT1 correlations were found with hospitalization duration, pre-existing conditions, or neuro-(psycho)logical tests.
Authors
- Christophe Théo Arendt (ORCID: https://orcid.org/0000-0003-3300-3729)
- Michael Ronellenfitsch (ORCID: https://orcid.org/0000-0002-1402-6290)
- Masia Fahim
- Kolja Jahnke (ORCID: https://orcid.org/0000-0003-1839-4055)
- Ulrich Pilatus (ORCID: https://orcid.org/0000-0002-3207-7796)
- Julia Koepsell (ORCID: https://orcid.org/0000-0003-1184-5327)
- Svenja Klinsing (ORCID: https://orcid.org/0000-0001-5051-6839)
- Alina Jurcoane (ORCID: https://orcid.org/0000-0001-5571-9635)
- Ralf Deichmann (ORCID: https://orcid.org/0000-0002-4110-1225)
- Maria J. G. T. Vehreschild (ORCID: https://orcid.org/0000-0003-0446-3224)
- Elke Hattingen (ORCID: https://orcid.org/0000-0002-8392-9004)
- Jan Rüdiger Schüre
Institutions
- Goethe University Frankfurt (DE)
- University Hospital Frankfurt (DE)
Publication Details
- Journal
- European Radiology Experimental
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1186/s41747-025-00598-7
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsches Zentrum für Infektionsforschung
- Goethe-Universität Frankfurt am Main