Effects of dexmedetomidine and magnesium sulphate on controlled hypotension in FES surgeries

Rhinosinusitis often requires functional endoscopic sinus surgery (FESS) when medical management fails, and controlled hypotension minimizes blood loss and optimizes surgical conditions. Dexmedetomidine and magnesium sulphate are commonly used to achieve controlled hypotension. Therefore, it is of interest to compare their efficacy in FESS, randomizing 60 patients to receive either dexmedetomidine or magnesium sulphate. Intraoperative mean arterial pressure (MAP) was consistently lower in the dexmedetomidine group compared to the magnesium sulphate group (p<0.01). We show that dexmedetomidine demonstrated superior performance for controlled hypotension during FESS, potentially improving surgical conditions and patient outcomes.