Psychiatric conditions with a known pathogenesis: anti-NMDAr encephalitis in the field of pediatric and adolescent psychiatry

The relevance of studying mental disorders in anti-NMDA encephalitis is due to a number of aspects: psychopathological manifestations in anti-NMDA encephalitis are polymorphic and manifest in the form of an acute psychotic disorder resistant to neuroleptic therapy is not uncommon; cases with periodic course are described; patients of childhood, adolescence and young age are more predisposed to the development of the disease, the quality of prognosis is associated with early the beginning of pathogenetic immunosuppressive therapy. Objective: to describe psychopathological manifestations in autoimmune encephalitis in a group of adolescent patients. Material and methods: the clinical and dynamic features of the course of autoimmune anti-NMDA receptor encephalitis in the acute and recovery period in four adolescent patients were studied. Conclusion: the study revealed specific disorders characteristic of organic mental disorders in the acute period of the disease and symptom complexes that might determine the severity of the disease – reversible regression of the psyche, cognitive impairment, motor coordination disorders.