Klotho modulation by tempol: a potential therapeutic axis in sepsis
Tempol is a promising agent against sepsis-induced organ damage. This was evident in its cardiorenal protective effect, up-regulation of klotho, suppression of inflammation, oxidation, and apoptosis, and enhancement of the antioxidant status.
Authors
- Sara Mohamed Naguib Abdel Hafez (ORCID: https://orcid.org/0000-0003-3901-2802)
- Remon Roshdy Rofaeil (ORCID: https://orcid.org/0000-0002-0159-5937)
- Alaa Al‐Kadi
- Al‐Shaimaa F. Ahmed (ORCID: https://orcid.org/0000-0001-9875-6399)
- Mohamed M. Sayed‐Ahmed (ORCID: https://orcid.org/0000-0002-2179-8002)
- Aliaa Anter
Institutions
- Cairo University (EG)
- Children Cancer Hospital (EG)
- Deraya University
- Minia University (EG)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1186/s12872-025-04738-0
- Citations
- 2
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.86