Exploring sex-specific clinical features in Chinese patients with Takotsubo syndrome
Chinese TTS patients demonstrate unique clinical characteristics and in-hospital outcomes. Apart from the well-known fact that male with TTS has high-risk phenotype, our study newly identifies that TTS females with younger age or physical triggers also have worse prognosis, which warrants close attention and follow-up.
Authors
- Lingchun Lyu
- Charles Antzelevitch (ORCID: https://orcid.org/0000-0001-7349-1582)
- Zhenhua Shi (ORCID: https://orcid.org/0000-0001-7308-3239)
- Xiaoping Lin (ORCID: https://orcid.org/0000-0001-7985-652X)
- Wei Deng (ORCID: https://orcid.org/0000-0003-1778-2013)
- Wang Ling-lin
- Qing Zhou (ORCID: https://orcid.org/0000-0002-1917-5105)
- Guohua Fan (ORCID: https://orcid.org/0000-0003-2950-191X)
- Dan Hu (ORCID: https://orcid.org/0000-0002-0994-8434)
- Kan Liu (ORCID: https://orcid.org/0000-0001-5236-9166)
- Hong-Yi Duan
- Jinling Chen (ORCID: https://orcid.org/0000-0003-2992-6571)
- Héctor Barajas-Martínez (ORCID: https://orcid.org/0000-0002-2704-3807)
- Jinqiu Liu (ORCID: https://orcid.org/0009-0008-5459-5894)
- Hongning Song (ORCID: https://orcid.org/0000-0001-6949-6444)
- Zhengyang Yu (ORCID: https://orcid.org/0000-0002-9711-9459)
- Jing Chen (ORCID: https://orcid.org/0000-0002-9035-9126)
- Hong Jiang (ORCID: https://orcid.org/0000-0001-9481-9807)
- Dong Hu (ORCID: https://orcid.org/0000-0003-4281-9017)
- Changwu Xu (ORCID: https://orcid.org/0000-0003-2127-2753)
- Yan Huang (ORCID: https://orcid.org/0009-0004-4740-830X)
- Xinhong Yang
Institutions
- Union Hospital (HK)
- Thomas Jefferson University (US)
- Lankenau Institute for Medical Research (US)
- Dalian Medical University (CN)
- Washington University in St. Louis (US)
- Wuhan University (CN)
- Lankenau Heart Institute (US)
- Lishui Central Hospital (CN)
- Renmin Hospital of Wuhan University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Hubei University of Education (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1186/s12872-025-04788-4
- Citations
- 1
- Primary Topic
- Takotsubo Cardiomyopathy and Associated Phenomena
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- Wuhan University
- National Institutes of Health
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities
- Renmin Hospital of Wuhan University