New sesquiterpene derivatives from stems and leaves of <i>Smallanthus sonchifolius</i>

From the MeOH residue of <i>Smallanthus sonchifolius</i> stems and leaves, three new sesquiterpene derivatives, namely smallantholides A - C (<b>1 </b>-<b> 3</b>), and two know phenyl propanoid glycosides (<b>4</b> and <b>5</b>), were isolated using various chromatographic techniques. The structural elucidation was confirmed by spectroscopic methods including 1D, 2D NMR, CD and HR-TOF-MS. Moreover, the <i>in vitro α</i>-glucosidase inhibitory activity of <b>1 </b>-<b> 5</b> was also evaluated.

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Publication Details

Journal
Natural Product Research
Published
2025-07-05
DOI
https://doi.org/10.1080/14786419.2025.2528154
Primary Topic
Microbial Metabolites in Food Biotechnology
Type
article
Field-Weighted Citation Impact
0.00

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article

New sesquiterpene derivatives from stems and leaves of Smallanthus sonchifolius

Trần Thị Hồng Hạnh, Do Hoang Anh, Nguyễn Xuân Cường, Le Thi Vien et al.
Natural Product Research
Microbial Metabolites in Food Biotechnology
article

New sesquiterpene derivatives from stems and leaves of Smallanthus sonchifolius

Trần Thị Hồng Hạnh, Do Hoang Anh, Nguyễn Xuân Cường, Le Thi Vien, Nguyen The Cuong, Phạm Thị Mai Hương, Nguyen Hoai Nam
article en

Abstract

From the MeOH residue of <i>Smallanthus sonchifolius</i> stems and leaves, three new sesquiterpene derivatives, namely smallantholides A - C (<b>1 </b>-<b> 3</b>), and two know phenyl propanoid glycosides (<b>4</b> and <b>5</b>), were isolated using various chromatographic techniques. The structural elucidation was confirmed by spectroscopic methods including 1D, 2D NMR, CD and HR-TOF-MS. Moreover, the <i>in vitro α</i>-glucosidase inhibitory activity of <b>1 </b>-<b> 5</b> was also evaluated.

Natural Product Research
Institute of Chemistry (CN), Hồng Đức University (VN), Thanh Do University, Vietnam Academy of Science and Technology (VN)
Vietnam Academy of Science and Technology
Zero hunger
Openalex Percentile: Top 80%
Microbial Metabolites in Food Biotechnology
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