A two-sample Mendelian randomization study of atrial fibrillation screening, risk factor analysis, and serum uric acid levels
This article demonstrated a significant dose-response relationship between elevated serum UA levels and AF risk, further supporting serum UA as an independent risk factor for AF. Moreover, through MR analysis, the potential causal relationship between serum UA levels and AF was validated, providing a new perspective and basis for AF screening and early diagnosis.
Authors
- Zhenhua Shi (ORCID: https://orcid.org/0000-0001-7308-3239)
- Wuming Hu (ORCID: https://orcid.org/0000-0003-3257-6699)
- Ranran Xia (ORCID: https://orcid.org/0000-0002-5276-5617)
- K. Ye
Institutions
- Lishui Central Hospital (CN)
Publication Details
- Journal
- Journal of Cardiothoracic Surgery
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1186/s13019-025-03448-0
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.00