Hepatoblastoma regional trends: dynamic SDI & joinpoint regression analysis
HB remains a significant global health issue. Over the past 32 years, the global burden of HB has generally declined, but the rate of decline has slowed, with stark disparities between socioeconomic regions. Global cooperation is essential in addressing the challenges posed by HB. The rise in high-SDI areas highlights the need to distinguish diagnostic improvements from true incidence increases. The burden is particularly heavy in low-middle-SDI regions and certain geographical areas. Priorities include enhancing access to pediatric oncology care in low-resource settings, optimizing prenatal/postnatal screening, and addressing socioeconomic drivers of inequity to reduce HB's burden globally.
Authors
- Enyang He (ORCID: https://orcid.org/0000-0002-0824-7820)
- Jia Miao (ORCID: https://orcid.org/0000-0002-6267-4401)
- Zhenhua Guo (ORCID: https://orcid.org/0000-0003-0592-5988)
- Hualei Cui (ORCID: https://orcid.org/0000-0001-9959-5072)
- Wei Feng (ORCID: https://orcid.org/0000-0002-9993-8722)
- Wei Liu
- Wenjing Sun (ORCID: https://orcid.org/0000-0001-5638-5892)
- Hailan Zhao
- Yi-Xiang Wang (ORCID: https://orcid.org/0000-0002-4021-4228)
- Wei Zhao (ORCID: https://orcid.org/0000-0002-8520-2087)
Institutions
- Tianjin University (CN)
- Tianjin Children's Hospital (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1186/s12885-025-14566-2
- Citations
- 5
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 7.59
Funders
- Institute for Health Metrics and Evaluation
- Chongqing Medical University