Influence of hybrid modification on functional properties of a commercial bio-titanium alloy Ti6Al4V

• Research on hybrid modification of commercial titanium alloy Ti6Al4 based on Nd:YAG laser and micro-arc xodation process. • Improvement of corrosion resistance and electrochemical properties as a result of laser modification. • Manufacturing of a ceramic layer on the laser-modified Ti6Al4V surface enriched in bioactive ions. • Improved cellular C2C12 response as a result of laser-MAO hybrid modification by a highly developed surface morphology. Although Ti6Al4V is widely used, its surface still needs improvement for medical applications. Here alloy was modified by a two-step process: laser treatment followed by micro-arc oxidation (MAO). This aimed to create a rough surface enriched with bioelements such as sodium, phosphorus, and zinc. SEM analysis revealed a complex but uneven surface, suggesting good potential for further hybrid surface development. Laser treatment improved the alloy’s stability and corrosion resistance. Wettability tests confirmed full hydrophilicity, a key factor in cell response. Notably, the single- and double-modified samples without nZnO showed the best biological performance, likely due to their high hydrophilicit.