Mouse models of aortic dissection induced by β-aminopropionitrile combined with angiotensin II and the changes in their gut microbiota
BAPN at 1 g/kg/day combined with subcutaneous injection of Ang-II is a stable and efficient method to induce acute AD in mice. Dysbiosis occurred in all groups, with a high degree of consistency across construction strategies.
Authors
- Shijie Xin (ORCID: https://orcid.org/0000-0001-6278-8794)
- Jiawei Zhang (ORCID: https://orcid.org/0000-0001-5127-9142)
- Xuan Li (ORCID: https://orcid.org/0000-0002-2988-946X)
- Shihua Wu (ORCID: https://orcid.org/0000-0002-1669-7522)
- Bo Jiang (ORCID: https://orcid.org/0000-0001-5647-6890)
- Shuai Cheng (ORCID: https://orcid.org/0009-0009-5539-6683)
- Xinyu Hao
- Xueling Wang
Institutions
- Shenyang Center for Disease Control and Prevention (CN)
- First Hospital of China Medical University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- China Medical University (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1186/s12866-025-04105-1
- Citations
- 1
- Primary Topic
- Aortic Disease and Treatment Approaches
- Type
- article
- Field-Weighted Citation Impact
- 1.52