Predicting brain amyloid load with digital and blood-based biomarkers
The combination of MemTrax and BBMs provides an accurate, convenient, non-invasive, cost-effective and scalable way to estimate Aβ load, which provides an opportunity for mass screening and timely and accurate diagnosis of AD. Our findings could also facilitate more effective AD clinical management in the PCPs office worldwide for more equitable access to current standard of care.
Authors
- Xianbo Zhou (ORCID: https://orcid.org/0000-0003-3544-7497)
- Haifan Kong (ORCID: https://orcid.org/0000-0001-6973-1520)
- Ganqiang Liu
- Wei–Neng Chen (ORCID: https://orcid.org/0000-0003-0843-5802)
- Yang Long (ORCID: https://orcid.org/0000-0003-4605-4306)
- J. Wesson Ashford (ORCID: https://orcid.org/0000-0001-9600-6471)
- Michael F. Bergeron (ORCID: https://orcid.org/0000-0003-1377-0234)
- Xiangsong Zhang (ORCID: https://orcid.org/0000-0002-1730-9923)
- Curtis B. Ashford
- Fengjuan Su
- Xiaoli Yao (ORCID: https://orcid.org/0000-0003-2613-7956)
- Jiayi Zhou (ORCID: https://orcid.org/0000-0001-8865-3070)
- Li Feng (ORCID: https://orcid.org/0000-0001-5039-1255)
- Yifan Zheng (ORCID: https://orcid.org/0000-0002-5320-0095)
- Zhong Pei (ORCID: https://orcid.org/0000-0002-8425-2867)
- Yingying Fang (ORCID: https://orcid.org/0000-0002-6187-2908)
- Xinchong Shi
Institutions
- Kunming University (CN)
- Sun Yat-sen University (CN)
- University of Hartford (US)
- VA Palo Alto Health Care System (US)
- Kunming Medical University (CN)
- Shanghai FRP Research Institute (China) (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2025-07-05
- DOI
- https://doi.org/10.1186/s13195-025-01801-y
- Citations
- 4
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 5.88
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China